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Phenylbutazone

Basic Info

Model No.: USP

Product Description

Phenylbutazone raw powder

Standard: EP/ USP
purity:98%
Characteristics:A white or almost white, crystalline powder, practically insoluble in water, soluble in ether, sparingly soluble in alcohol. It dissolves in alkaline solutions… 

 

Synonyms:

4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione; 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

Molecular Weight:

308.379

Molecular Formula:

C19H20N2O2

Density:

1.542g/cm3

Melting Point(°C):

104-107°C

Boiling Point(°C):

401.7°C at 760 mmHg

Flash Point(°C):

179.9°C

refractive_index:

1.606

Water Solubility:

<0.1 g/100 mL at 23.5°C

 

Usage:  a drug used to treat certain types of cancer.   It is used in treating chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and some other diseases.

Appearance:white powder

Function:Treatment in Philadelphia chromosome (Ber-Abl) positive chronic myelogenous leukemia.Has effect in gastrointestinal stromal tumor therapy.

 

Appearance

Yellowish to white crystalline powder

Conforms

Solubility

Soluble in water and sparingly soluble in methanol

Conforms

Identification

NMR, HPLC,IR

Conforms

Loss on Drying

≤0.5%

032%

Residue on Ignition

≤ 0.2%

0.06%

Heavy Metals

≤ 20ppm

<20ppm

Related substances

 Total impurity ≤1.5%

Single impurity: ≤0.5%

0.88%

0.26%

Assay

≥98.5%

99.0%

 

Storage:Kept in dry and ventilating place, low tempeture ,prevent from rain and moisture.

 

 

 

 


 

 

 

 

 

 

 

 

 

  
 
 

 

 
 
 

 

 

 

 

 

 

 

 

 

 

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Product Categories : Pharmaceutical Raw Materials